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To determine whether GSSG-induced TNF hepatotoxicity is associated with inhibition of the NF-B signaling pathway, we first examined the effects of H 2 O 2 , BCNU, and diamide treatment on TNF-stimulated NF-B activation

Glutathione is a powerful antioxidant that may support individuals looking to maintain overall health and well-being

Liver & Kidney Stress, Organ Toxicity A controlled clinical study (treatment group: 1,200 mg IV twice a week for six weeks) comparing glutathione vs placebo found that 8 out of 16 participants developed deranged liver function tests

This doesn't mean it's unsafe it means it hasn't gone through the specific regulatory pathway the FDA requires for approved drugs